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Table 2: The association between risk factors and the presence of calcifications in the intracranial internal carotid artery
Variable Odds Ratios Adjusted for Age and Sex Odds Ratios Adjusted for Age, Sex, and All Risk Factors
Odds Ratio (95% CI) P Value Odds Ratio (95% CI) P Value
A 
    Smoking (ever) 1.7 (1.0–2.8) .04 1.9 (1.1–3.3) .01
    Hypertension 1.8 (1.1–3.1) .03 1.6 (0.9–2.8) .11
    Hypercholesterolemia 2.0 (1.1–3.8) .02 1.9 (1.0–3.7) .04
    Diabetes 1.7 (0.8–3.4) .15 1.6 (0.8–3.4) .21
    History of cardiac disease 2.3 (1.3–4.2) <.01 2.1 (1.1–4.0) .02
    History of cerebrovascular disease 1.2 (0.7–2.0) .59 1.0 (0.6–1.9) .93
B 
    Smoking (ever) 1.5 (0.9–2.5) .14 1.4 (0.8–2.4) .20
    Hypertension 1.2 (0.6–2.1) .63 1.0 (0.5–1.8) .90
    Hypercholesterolemia 1.7 (0.9–3.3) .11 1.7 (0.9–3.4) .13
    Diabetes 1.4 (0.7–2.6) .33 1.3 (0.7–2.6) .44
    History of cardiac disease 2.2 (1.3–3.7) <.01 2.0 (1.2–3.5) .01
    History of cerebrovascular disease 2.0 (1.2–3.4) .01 1.9 (1.1–3.3) 0.03
Note:—CI indicates confidence interval; A, presence of calcifications versus absence; B, upper quartile versus lower 3 quartiles.