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Table 2: Cluster localizations of the substantia nigra group-analysis P < .01, k = 50 MNI coordinates (mm)
BA Brain Region
Primary Peak Locations
Right Side Left Side
x y z x y z
Left substantia nigra
Prefrontal cortex 11/47 37.44 28.08 –4.00 –32.76 28.08 –8.00
Frontal cortex 6 m 11.70 11.70 48.00 –7.02 2.34 48.00
4 46.80 –7.02 44.00 – – –
Orbitofrontal cortex 25 4.68 9.36 –16.00 –2.34 9.36 –13.00
Occipital cortex 19/39 44.46 –79.56 32.00 – – –
Temporal cortex 21 53.82 –11.70 –12.00 –51.48 –16.38 –8.00
Hippocampus 35 21.06 –35.10 –12.00 –16.38 –39.78 –12.00
Insula 13 44.46 4.68 –4.00 –30.42 9.36 –4.00
Lentiform nucleus 28.08 11.70 –4.00 –28.08 14.04 00.00
Thalamus 16.38 –16.38 00.00 –11.70 –18.72 4.00
Hypothalamus 7.02 –2.34 –12.00 –2.34 –2.34 –16.00
Mesencephalic tegmentum 4.68 –30.42 –20.00 –4.68 –28.08 –16.00
Pons 00.00 –32.76 –24.00 – – –
Right substantia nigra
Prefrontal cortex 46 46.80 39.78 20.00 
11 (/47) 32.76 25.74 –8.00 –25.74 23.40 –16.00
9 (/6) 51.48 18.72 40.00 – – –
8 4.68 37.44 40.00 –2.34 37.44 44.00
Orbitofrontal cortex 25 7.02 9.36 –12.00 –4.68 9.36 –12.00
Motor cortex 4 51.48 –9.36 40.00 –56.16 –4.68 24.00
Cingulate cortex 24 (/32) 8.27 44.26 20.29 –2.34 37.44 8.00
Hippocampus 35 11.70 –39.78 –12.00 –23.40 –25.74 –12.00
Insula 13 39.78 –4.68 8.00 –41.59 11.70 2.00
Lentiform nucleus 25.74 4.68 –4.00 –25.74 11.70 –8.00
Caudate nucleus 9.60 11.30 2.92 –11.70 16.38 00.00
Claustrum 32.76 14.04 –4.00 –32.76 –11.70 –8.00
Thalamus 15.62 –14.34 4.00 –11.03 –16.17 4.00
Hypothalamus 11.70 –4.68 –8.00 –4.68 –4.68 –8.00
Mesencephalic tegmentum 7.02 –30.42 –20.00 –2.34 –28.08 –20.00
Cerebellum (vermis) 11.70 –56.16 –28.00 –4.68 –60.84 –24.00