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Table 2: Effect of sequence parameters, section thickness, and field strength on CI and diameter of microbleeds
Comparator Parameters No. of CMB (No. of subjects) Mean ± SD P Value Cohen D
GRE vs SWI 
    At 1.5T thin-section 170 (5) GRE SWI 
        CI 0.40 ± .16 0.65 ± .10 <.0001 1.87
        Diameter (mm) 2.51 ± .87 2.76 ± .94 <.0001 0.28
    At 1.5T thick-section 79 (3) GRE SWI 
        CI 0.25 ± .15 0.49 ± .14 <.0001 1.65
        Diameter (mm) 3.03 ± 1.32 3.35 ± 1.69 .0004 0.21
Thick vs Thin Sections 
    At 1.5T GRE 138 (5) Thick section Thin section 
        CI 0.20 ± .14 0.40 ± .15 <.0001 1.38
        Diameter (mm) 3.07 ± 1.76 2.51 ± 0.85 <.0001 0.41
    At 1.5T SWI 79 (2) Thick section Thin section 
        CI 0.49 ± .18 0.67 ± .10 <.0001 1.24
        Diameter (mm) 3.21 ± 1.76 2.94 ± 1.28 .0037 0.18
1.5T vs 3T 
    At thick-section GRE 119 (4) 1.5T 3T 
        CI 0.23 ± .14 0.34 ± .17 <.0001 0.71
        Diameter (mm) 3.09 ± 1.41 3.45 ± 1.50 <.0001 0.25
    At thin-section SWI 29 (1) 1.5T 3T 
        CI 0.67 ± .07 0.73 ± .06 .0001 0.88
        Diameter (mm) 2.50 ± 0.66 2.26 ± 0.55 .0001 0.40
Note:—CI indicates contrast index; CMB, cerebral microbleeds.