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Measurements of FA, axial, and radial diffusivities*
Axial Diffusivity (10⁻³ s/mm²) Radial Diffusivity (10⁻³ s/mm²) FA
3 weeks 1 year 2 years 3 weeks 1 year 2 years 3 weeks 1 year 2 years
SCC 2.30 ± 0.1 1.90 ± 0.09 1.93 ± 0.1 0.79 ± 0.1 0.35 ± 0.06 0.33 ± 0.06 0.60 ± 0.05 0.8 ± 0.03 0.81 ± 0.03
(0.83) (0.84) (0.44) (0.42) (1.33) (1.35)
BCC 2.06 ± 0.1 1.91 ± 0.07 1.93 ± 0.06 1.0 ± 0.1 0.58 ± 0.09 0.4 ± 0.03 0.44 ± 0.05 0.65 ± 0.05 0.71 ± 0.07
(0.81) (0.8) (0.53) (0.45) (1.3) (1.37)
GCC 2.26 ± 0.14 1.82 ± 0.07 1.80 ± 0.05 0.89 ± 0.13 0.47 ± 0.07 0.40 ± 0.08 0.54 ± 0.05 0.7 ± 0.04 0.74 ± 0.05
(0.93) (0.94) (0.58) (0.4) (1.48) (1.61)
CST 1.81 ± 0.09 1.71 ± 0.07 1.75 ± 0.06 0.88 ± 0.06 0.57 ± 0.05 0.49 ± 0.12 0.44 ± 0.03 0.62 ± 0.03 0.67 ± 0.04
(0.89) (0.88) (0.67) (0.98) (1.18) (1.19)
OR 1.86 ± 0.09 1.60 ± 0.05 1.58 ± 0.05 0.90 ± 0.08 0.71 ± 0.05 0.51 ± 0.08 0.43 ± 0.03 0.49 ± 0.03 0.53 ± 0.03
(0.94) (0.97) (0.65) (0.56) (1.41) (1.52)
IC 1.76 ± 0.04 1.56 ± 0.04 1.54 ± 0.04 0.64 ± 0.04 0.43 ± 0.02 0.63 ± 0.04 0.57 ± 0.03 0.67 ± 0.02 0.68 ± 0.03
(0.86) (0.85) (0.79) (0.57) (1.14) (1.23)
PPW 1.89 ± 0.13 1.47 ± 0.09 1.43 ± 0.08 1.14 ± 0.08 0.78 ± 0.05 0.7 ± 0.04 0.32 ± 0.03 0.4 ± 0.05 0.44 ± 0.04
(0.78) (0.76) (0.68) (0.61) (1.25) (1.38)
FPW 1.76 ± 0.17 1.33 ± 0.05 1.22 ± 0.06 1.28 ± 0.13 0.78 ± 0.04 0.70 ± 0.05 0.22 ± 0.02 0.34 ± 0.03 0.36 ± 0.05
(0.76) (0.69) (0.61) (0.55) (1.55) (1.64)
Note:—FA indicates fractional anisotropy; SCC, splenium of corpus callosum; BCC, body of corpus callosum; GCC, genu of corpus callosum; CST, corticospinal tract; OR, optic radiation; IC, posterior limb of internal capsule; PPW, posterior peripheral white matter; FPW, frontal peripheral white matter.
* The values are expressed as mean ± SD. Both the 1- and 2-year-old values are normalized to the corresponding values of the neonates for each region, and the results are provided in the parentheses.