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Table 1: 
Demographics, quantitative CT measurements, and categoric variables in patients with Graves ophthalmopathy, with and without ON*
Graves OphthalmopathyONWithout ONP Value
Demographics
    No. orbits3250
    Age55.9 ± 11.5 (39–78)44.7 ± 11.0 (28–65)
    Sex (male, female)14 M, 18 F20 M, 30 F
Bony confines
    Bony orbital angle (degrees)
        Orbital rim42.4 ± 2.5 (39–49)42.2 ± 2.4 (37–51)<.727
        Medial wall-0.1 ± 5.7 (−8–12)−3.6 ± 5.2 (−13–12)<.006
        Lateral wall6.7 ± 3.0 (1–13)4.7 ± 2.5 (1–11)<.002
        Total angular change6.6 ± 7.5 (−3–20)1.1 ± 6.5 (−8–17)<.001
        Orbital apex49.0 ± 8.2 (38–65)43.3 ± 7.4 (30–59)<.002
    Length of lateral wall (mm)44.1 ± 2.9 (35.7–48.9)42.5 ± 3.2 (33.7–47.5)<.022
Extraoccular muscles (mm)
    Maximum muscle diameter
        Medial rectus7.2 ± 1.8 (3.8–10.5)4.8 ± 1.8 (2.6–10.0)<.0005
        Lateral rectus4.9 ± 1.5 (2.3–8.2)3.8 ± 0.9 (2.1–6.4)<.0005
        Superior muscle group6.5 ± 1.8 (3.6–9.5)4.9 ± 1.7 (2.6–8.7)<.0005
        Inferior rectus7.1 ± 2.0 (3.2–12.8)5.0 ± 1.6 (2.6–9.5)<.0005
        Superior oblique3.0 ± 0.7 (1.8–4.5)2.8 ± 0.7 (1.8–4.4).212
        MDI29.0 ± 5.2 (21.1–42.3)21.2 ± 4.8 (14.3–32.3)<.0005
    Medial rectus bulk from IZ line14.0 ± 3.9 (5.4–21.0)12.3 ± 3.4 (6.0–21.2).049
    Lateral rectus bulk from IZ line16.0 ± 3.0 (10.8–21.2)14.8 ± 2.8 (10.7–21.1).084
Neurovascular structures
    Proptosis from IZ line2.6 ± 2.7 (−3.5–7.0)3.5 ± 4.0 (−4.6- 12.7).200
    Optic nerve stretch40.8 ± 3.2 (35.0–47.9)39.7 ± 4.1 (30.7–46.6).243
    Optic nerve sheath
        Retrobulbar5.7 ± 0.7 (4.2–7.2)5.8 ± 0.9 (4.0–8.1).464
        Waist3.7 ± 0.6 (2.4–5.2)3.6 ± 0.7 (1.6–5.5).703
    Superior ophthalmic vein1.9 ± 0.4 (1.2–2.7)1.8 ± 0.4 (1.2–2.9).273
Apical crowding3 (1–3)1 (0–3)<.0005†
Presence of intracranial fat prolapse11 (34.4%)13 (26.0%).416‡
  • Note:—IZ line indicates interzygomatic line; ON, optic neuropathy; MDI, muscle diameter index.
  • * Descriptive statistics presented are mean ± SD (range) and count (%) for the presence of intracranial fat prolapse. All mean quantitative CT measurements between the 2 groups are compared using the Student 2-tailed t test. Statistical significance is defined at P < .05.
  • † The categoric variables are compared using the Mann-Whitney U test. Statistical significance is defined at P < .05.
  • ‡ The categoric variables are compared using the χ2 square test. Statistical significance is defined at P < .05.