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Table 2: Mean NAA/Cr, Cho/Cr, and mIns/Cr ratios obtained from the WM of healthy subjects, NAWM in MS, CDL, and EDL
VOI Site NAA/Cr (P^* Value) Cho/Cr (P^* Value) mIns/Cr (P^* Value)
WM of healthy subjects 1.610 1.016 0.414
(.704)^† (.810)^† (.907)^†
(.175)^‡ (.211)^‡ (.003)^‡
(.279)^§ (.326)^§ (.849)^§
NAWM in MS 1.560 1.033 0.411
(.704)^* (.810)^* (.907)^*
(.647)^‡ (.111)^‡ (.000)^‡
(.845)^§ (.939)^§ (.423)^§
CDL 1.452 1.110 0.557
(.175)^* (.211)^* (.003)^*
(.647)^† (.111)^† (.000)^†
(.917)^§ (.928)^§ (.097)^§
EDL 1.455 1.120 0.404
(.279)^* (.326)^* (.848)^*
(.845)^† (.940)^† (.423)^†
(.917)^‡ (.928)^‡ (.097)^‡
Note:—NAA indicates N-acetylaspartate; Cr, creatine; Cho, choline; mIns, myo-inositol; WM, white matter.
* Value in comparison with the WM of healthy subjects.
† P value in comparison with the NAWM of MS.
‡ P value in comparison with CDL.
§ P value in comparison with EDL.