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Cortical hamartoma perfusion imaging findings in a series of 13 patients evaluated with pulsed arterial spin-labeling
Pt Age (yr) Seizures per Week Seizure Frequency No. Cortical Hamartomas >1 cm No. Hyperperfused Hamartomas No. Hypoperfused Hamartomas No. Normally Perfused Hamartomas Mean Normal GM Perfusion (mL/100 g/min) Mean Hyperperfused Lesions (mL/100 g/min) Mean Hypoperfused Lesions (mL/100 g/min)
1a 0.7 0 None 12 0 11 1 63.8 26.5
1b 12 0 11 1 67.9 26.3
2a 7 0 None 10 0 10 0 116.6 63.8
2b 9 0 6 3 123.0 79.8
3 2 1 1 per week 21 0 21 0 173.6 104.6
4a 8 2 2 per week, left facial twitch 9 3 5 1 108.1 155.1 68.1
4b 9 3 6 0 112.4 154.0 35.3
5 7 0 None, last 8 months 3 1 2 0 102.3 127.7 86.7
6 23 4 4 per week, EEG left temporal 23 1 21 1 52.8 61.4 20.0
7 5 0 None, last 3 months 41 0 41 0 131.4 23.0
8 3 3 3–4 per week 18 1 17 0 163.2 186.7 61.6
9 12 0 None last 10 years 5 0 5 0 85.4 25.6
10 6 0 None last 2 years 22 1 21 0 122.2 151.2 45.2
11 3 0 None last 3 months 19 0 18 1 99.6 38.9
12 10 0 None last 3 months 8 0 8 0 84.6 22.8
13 11 2 1–2 per week 24 0 24 0 60.0 23.8
Note:—Pt indicates patient; EEG, electroencephalogram; GM, gray matter.