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Table 2: 
ROC curve analysis results for the prediction of response to induction chemotherapy based on the pretreatment tumor volume and the perfusion-associated parameters*
ResponseCutoff ValueSensitivity (%)Specificity (%)AUCP Value
Pretreatment tumor volume (mL)≤15.3100 (99.1–100)33.3 (26.5–40.7)0.50.84
Blood flow (mL/100 g/min)≤66.284.2 (79.8–89.7)66.7 (59.3–73.5)0.63.0001
Blood volume (mL/100 g)>7.4100 (98.9–100)30.6 (23.9–37.8)0.59.0005
Mean transit time (s)<8.543.7 (38.4–49.1)100 (98–100)0.62.0001
Permeability (mL/100 g/min)>8.665.4 (60.1–70.4)100 (98–100)0.78.0001
  • Note:—AUC indicates area under the curve.
  • * The values (95% CI) represent thresholds above or below of which the patients will show a response.