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Table 2: ICC and 95% CIs for inter- and intraobserver measurements of BF, BV, MTT, and PS
Perfusion Parameter ICC 95% CI
Interobserver: expert reader A vs nonexperienced reader 
    BF 0.98 0.95–0.99
    BV 0.88 0.76–0.95
    MTT 0.78 0.57–0.90
    PS 0.67 0.39–0.84
Interobserver: expert reader B vs nonexperienced reader 
    BF 0.99 0.99–1.00
    BV 0.91 0.80–0.96
    MTT 0.77 0.55–0.89
    PS 0.94 0.87–0.97
Interobserver: expert reader A vs expert reader B 
    BF 0.98 0.96–0.99
    BV 0.95 0.88–0.98
    MTT 0.94 0.87–0.97
    PS 0.65 0.36–0.82
Intraobserver: expert reader A 
    BF 0.99 0.98–1.00
    BV 0.95 0.93–0.98
    MTT 0.97 0.95–0.99
    PS 0.70 0.55–0.83
Intraobserver: expert reader B 
    BF 1.00 0.99–1.00
    BV 0.99 0.98–0.99
    MTT 0.94 0.90–0.97
    PS 0.87 0.79–0.93
Note:—ICC indicates interclass correlation coefficient; CI, confidence interval; BF, blood flow; BV, blood volume; MTT, mean transit time; PS, permeability surface area product.