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Correlations of MTR measurements and cognitive status measures
Whole Brain MTR Localized MTR
Mmtr NPH PSite Genu Splen FWM CSEM Put Caud Thal
MSK −0.64^* −0.57^* −0.36 −0.61^* −0.53^* −0.46^* −0.38 −0.51^* −0.39 −0.51^*
Working memory 0.03 −0.51 0.32 0.11 0.29 0.25 0.31 0.06 0.08 0.09
Verbal memory −0.14 0.51 −0.24 −0.23 −0.01 −0.28 −0.32 −0.02 −0.33 −0.05
Visual memory 0.47 0.18 0.25 0.48^* 0.48^* 0.42 0.46^* 0.10 0.30 0.30
Visuoconstruction 0.43 −0.05 0.43 0.49^* 0.20 0.56^* 0.54^* 0.28 0.41 0.37
Psychomotor 0.11 0.27 0.07 0.24 0.19 0.04 −0.12 0.15 −0.25 0.23
Motor speed 0.40 0.46 0.11 0.24 0.54^* 0.24 0.11 0.26 0.05 0.42
Executive function −0.26 0.14 −0.25 −0.37 −0.14 −0.26 −0.22 −0.36 −0.24 −0.16
Note:—Mmtr = mean MTR; NPH, normalized peak height; Psite, peak site; Splen, splenium; FWM, frontal white matter; CSEM, centrum semiovale; Put, putamen; Caud, caudate; Tha; thalamus.
* Significant using FDR-adjusted P value. Spearman correlation coefficients for MSK; all others, Pearson correlation coefficients.