Table 3:

Cervical cord atrophy and lesion MR imaging measures in normal control subjects and multiple sclerosis patients, according to disease type

Variable	NC (n= 19), Mean (SD)	MS (n= 66), Mean (SD)	CIS (n= 11), Mean (SD)	RR (n= 34), Mean (SD)	SP (n= 14), Mean (SD)	PP (n= 7), Mean (SD)
CCAV, mm³	7691.7 (1136.2)	7063.2 (1206.8)^**	7461.1 (599.5)	7281.6 (758.9)	5990.7 (1060.9)^***	6907.3 (1796.2)^*
CCF	0.343 (0.29)	0.318 (0.23)^**	0.344 (0.04)	0.307 (0.06)	0.307 (0.06)^*	0.294 (0.04)^*
CCAV/ICV	0.012 (0.002)	0.016 (0.02)	0.012 (0.002)	0.015 (0.005)	0.015 (0.016)	0.01 (0.005)
Cervical T2-LV, mL	NA	4.6 (5.8)	0.7 (0.02)	4.2 (3.8)	9.7 (8)	2.6 (3.2)

Note:—NC indicates normal control subject; MS, multiple sclerosis; RR, relapsing-remitting; SP, secondary-progressive; PP, primary-progressive; CIS, clinically isolated syndrome; CCAV, cervical cord absolute volume; CCF, cervical cord fraction; CCAV/ICV, cervical cord absolute volume to intracranial volume; LV, lesion volume; NA, nonapplicable. A general linear model analysis was performed to test significant differences between normal control subjects and multiple sclerosis patients in which the age was entered as a covariate and, due to the multiple comparisons, a post hoc Bonferroni correction was applied directly in the SPSS analysis model.
P values are provided between normal control subject and multiple sclerosis patients
* P < .05;
** P < .01;
*** P < .001.