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Table 4: Brain MR imaging measures in normal control subjects and multiple sclerosis patients, according to disease type
Variable NC (n= 19), Mean (SD) MS (n= 66), Mean (SD) CIS (n= 11), Mean (SD) RR (n= 34), Mean (SD) SP (n= 14), Mean (SD) PP (n= 7), Mean (SD)
BPF 0.845 (0.006) 0.827 (0.02) 0.834 (0.01) 0.832 (0.01) 0.815 (0.02) 0.815 (0.009)
MPD, × 10⁻⁶ mm²/s 1130.1 (65.8) 1204.3 (89.2) 1143.4 (59.1) 1222.8 (100.4) 1196.3 (71) 1222.9 (61)
T2-LV, mL NA 11 (12.6) 5.1 (6.5) 12.1 (14.4) 18.3 (13.5) 6.9 (7.7)
T1-LV, mL NA 1.7 (3.2) 0.5 (0.7) 1.2 (1.7) 3.2 (5.4) 1.2 (1.5)
Note:—NC indicates normal control subjects; MS, multiple sclerosis; RR, relapsing-remitting; SP, secondary-progressive; PP, primary-progressive; CIS, clinically isolated syndrome; BPF, brain parenchyma fraction; MPD, mean parenchyma diffusivity; LV, lesion volume; NA, nonapplicable.