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Table 4: VBM results of contrast between MCI converters and MCI nonconverters (no covariates)*
MNI Max pCluster K T pFDR Cluster % R/L Location
−58 0 -15 0.0001 5240 (5.2 cm³) 5.1 0.04 46.51 Left Superior temporal gyrus
40.88 Left Middle temporal gyrus
6.16 Left Superior temporal pole
5.23 Left Middle temporal pole
−24 -4 -24 0.002 3220 (3.2 cm³) 4.7 0.04 57.30 Left Hippocampus
21.46 Left Parahippocampal gyrus
10.09 Left Fusiform gyrus
6.27 Left Amygdala
4.41 Left Middle temporal pole
−52 -64 38 0.05 1524 (1.5 cm³) 4.7 0.04 67.78 Left Angular gyrus
29.27 Left Inferior parietal lobule
2.95 Left Supramarginal gyrus
56 12 -17 0.04 1627 (1.6 cm³) 4.5 0.04 47.80 Right Middle temporal gyrus
22.54 Right Superior temporal pole
16.40 Right Inferior temporal gyrus
6.63 Right Superior temporal gyrus
5.12 Right Middle temporal pole
Note:—pCluster indicates p cluster corrected; K, cluster size; T, T value; pFDR, p false discovery rate; MCI, mild cognitive impairment; MNI, Montreal Neurologic Institute.
* Statistics calculated within a brain mask excluding the cerebellum. Thresholding was performed at P < .0001 (uncorrected) and subsequently only the cluster surviving corrected thresholds reported pCluster = .1, pFDR voxel corrected = .1, cluster extent = 70 = 0.7 cm³.