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Table 5: VBM results of the comparison between MCI converters and MCI nonconverters adjusting for gender, age, global gray matter volume, and delayed NYU paragraph recall*
MNI Max pCluster K T pFDR Cluster % R/L Location
−34 -57 51 0.07 931 (0.9 cm³) 5 0.06 70.03 Left Angular gyrus
29.22 Left Inferior parietal lobule
−54 -42 10 0.06 941 (0.9 cm³) 4.4 0.06 81.08 Left Superior temporal gyrus
18.92 Left Middle temporal gyrus
Note:—pCluster indicates p cluster corrected; K, cluster size; T, T value; pFDR, p false discovery rate; VBM, voxel-based morphometry; MCI, mild cognitive impairment; MNI, Montreal Neurologic Institute.
* Statistics calculated within a brain mask comprising only temporal and parietal lobes. Thresholding was performed at P < .0001 (uncorrected), and subsequently only the cluster surviving corrected thresholds reported pCluster = .1, pFDR voxel-level corrected = .1, cluster extent = 70 = 0.7 cm³.