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Table 2:

Multivariate analysis of specific prognostic factors

Prognostic FactorHazard Ratio* (95% CI)P Value
Age ≥50 yearsNA.814
Sex: male2.632 (1.153–6.010).021
Histologic diagnosis of GBM9.707 (3.163–29.788)<.001
Neurologic function: home or hospitalNA.435
Abnormal mental statusNA.228
KPS score ≤ 80NA.150
Extent of surgery: biopsy2.692 (1.196–6.061).016
Tumor enhancement: presentNA.726
rCBV > 2.34.739 (1.950–11.518)<.001
  • Note:—NA indicates not applicable; GBM, glioblastoma multiforme; KPS, Karnofsky performance scale; rCBV, relative cerebral blood volume.

  • * Hazard ratio was not calculated when P ≥ .05.

  • Neurologic function is limited so that the patient is either confined to the home or hospitalized.