1naresh
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Variable IV + Intervention IV Only P Effect Size† No. patients 33 30 Admission NIHSS score‡ (mean ± SD) 15.8 ± 3.5 16.0 ± 3.5 Admission NIHSS score (median, 25%, 75%) 15 (13, 19) 16.5 (14, 18.75) .822 0.033 Follow-up NIHSS score 8 (2, 14) 14 (11.5, 7) .037 0.535 NIHSS score improvement 9 (2, 12) 12 (3.5, −22) .025 0.575 Significance of change from admission P = .071 P = .173 ≥4 NIHSS points 22 (66.7) 15 (50%) .208 2.00 (0.72–5.53) ≥10 NIHSS points 16 (48.5%) 7 (23.3%) .066 3.09 (1.04–9.17) Favorable outcome (NIHSS scores, 0–2) 11 (33.3%) 4 (13.3%) .080 3.25 (0.91–11.66) 90-Day mortality 4 (12.1%) 12 (40.0%) .019 0.21 (0.06–0.74)
Note:—NIHSS indicates National Institutes Health Stroke Scale.
* Follow-up assessment performed at day 7 or discharge for the intervention group and discharge or follow-up visit for the control group (see text).
† Effect size measured as Cohen D for continuous variables or odds ratio (95% CI) for categoric variables.
‡ Admission NIHSS scores for all patients ≥10.