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Model inputs analysis for base case and range of univariate sensitivity
Model Input Aggressive NIR Rx (range) Best Medical Therapy (range) Reference
Recanalization rate 84% (63%–100%) 24% (14%–50%) Rha and Saver, 2007⁹
Symptomatic ICH 
    With recanalization 6.2% (4%–14%) 2.0% Smith et al, 2008¹²; Furlan et al, 1999¹⁵
    Without recanalization 17.3% 5.5% Smith et al, 2008¹²; Furlan et al, 1999¹⁵
Relative utility 
    Permanent mild disability (mRS 0–2) 0.85 0.85 Earnshaw et al, 2006¹⁹
    Permanent moderate-severe disability (mRS 3–5) 0.27 0.27 Earnshaw et al, 2006¹⁹
    Death 0 0 
Costs 
    With ICH complication $28,087 $10,245 Medicare MS-DRG 023 and 064¹⁶
    Without ICH complication $19,210     $4,686 Medicare MS-DRG 024 and 066¹⁶
    Mild disability (annual) $2,200 $2,200 Gage et al, 1995²⁹
    Moderate-severe disability (annual) $20,000 $20,000 Gage et al, 1995²⁹
    Discount rate 3.00% 3.00% Gold et al, 1996¹³