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Demographic and peri-interventional data of the patient cohort
Demographics Data
No. of patients 133
Women 77
Men 56
Mean age (yr) 69.18 ± 11.45 (range, 22–90)
ASA Score 
    ASA 1 3 (2.3%)
    ASA 2 31 (23.3%)
    ASA 3 68 (51.1%)
    ASA 4 31 (23.3%)
No. of vertebrae treated 162
    1 VB per session 113
    2 VBs per session 11
    3 VBs per session 9
Time of intervention (mean min) 64.2 ± 25.6
    1 VB treated per session 57.9 ± 24.2
    2 VBs treated per session 65.6 ± 28.8
    3 VBs treated per session 70.0 ± 24.9
Amount of piritramid (mg) (mean total) 11.8 ± 3,98
    1 VB 11.41 ± 4.29
    2 VBs 12.6 ± 3.0
    3 VBs 13.11 ± 3.4
Amount of midazolam (mg) (mean total) 11.3 ± 4.38
    1 VB 10.8 ± 4.4
    2 VBs 11.9 ± 3.8
    3 VBs 14.0 ± 3.9
Etiology of vertebral fracture 
    Osteoporosis 86 (64.7%)
    Metastasis of unknown primary 6 (4.5%)
    Metastasis of known primary 22 (16.5%)
    Plasmocytoma 15 (11.3%)
    Lymphoma 4 (3%)

Demographics	Data
No. of patients	133
Women	77
Men	56
Mean age (yr)	69.18 ± 11.45 (range, 22–90)
ASA Score
ASA 1	3 (2.3%)
ASA 2	31 (23.3%)
ASA 3	68 (51.1%)
ASA 4	31 (23.3%)
No. of vertebrae treated	162
1 VB per session	113
2 VBs per session	11
3 VBs per session	9
Time of intervention (mean min)	64.2 ± 25.6
1 VB treated per session	57.9 ± 24.2
2 VBs treated per session	65.6 ± 28.8
3 VBs treated per session	70.0 ± 24.9
Amount of piritramid (mg) (mean total)	11.8 ± 3,98
1 VB	11.41 ± 4.29
2 VBs	12.6 ± 3.0
3 VBs	13.11 ± 3.4
Amount of midazolam (mg) (mean total)	11.3 ± 4.38
1 VB	10.8 ± 4.4
2 VBs	11.9 ± 3.8
3 VBs	14.0 ± 3.9
Etiology of vertebral fracture
Osteoporosis	86 (64.7%)
Metastasis of unknown primary	6 (4.5%)
Metastasis of known primary	22 (16.5%)
Plasmocytoma	15 (11.3%)
Lymphoma	4 (3%)