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Table 1: Demographic and clinical characteristics of patients with SCA3 and SCA6 (mean ± SD, range)
SCA3 (n = 17) SCA6 (n = 17) Difference of Mean SCA3 vs SCA6^a
Age (yr) 49.8 ± 11.5 (27–67) 65.8 ± 6.5 (52–75) P = .008^b
Sex (M/F) 10:7 11:6 
Disease duration (yr) 6.4 ± 4.8 (0–18) 8.9 ± 5.7 (1–23) N.S.
Age at onset (yr) 43.4 ± 12.3 (19–62) 55.6 ± 8.7 (41–67) P = .004^b
CAG repeat length 68.7 ± 3.5 (58–73) 21.6 ± 0.7 (21–22) N.A.
ICARS 34.7 ± 10.8 (17–60) 30.6 ± 10.9 (15–46) N.S.
    I) Posture and gait 11.0 ± 7.8 (2–29) 9.0 ± 5.2 (3–23) P = .043^c
    II) Kinetic functions 13.0 ± 4.8 (2–24) 13.0 ± 6.1 (5–32) N.S.
    III) Speech 3.0 ± 1.5 (0–5) 3.0 ± 1.6 (0–6) N.S.
    IV) Oculomotor 4.0 ± 1.5 (0–6) 5.0 ± 1.2 (2–6) N.S.


a Statistically significant differences between the SCA3 and SCA6 patient groups under consideration of the disease duration; analysis of variance (GLM model) with disease duration as a covariable.


b Significant with P< .01.


c Significant with P < .05.