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Table 5: Ordinal regression between ICARS subscore groups and CNS volumes: simple ordinal regression and ordinal regression including disease duration (DD) as a covariate
Regression Type SCA Cerebellum Brain Stem
Simple Ps.R²P Including DD Ps.R²P Simple Ps.R²P Including DD Ps.R²P
I) Posture and gait 3 0.35 0.018^a 0.45 0.10 0.23 0.025^a 0.41 0.11
6 0.41 0.010^a 0.43 0.062 0.23 0.044^a 0.36 0.10
II) Kinetic functions 3 0.05 0.32 0.065 0.72 0.14 0.14 0.14 0.19
6 0.21 0.053 0.27 0.29 0.29 0.025^a 0.40 0.048^a
III) Speech functions 3 0.08 0.26 0.49 0.62 0.03 0.52 0.51 0.32
6 0.30 0.036^a 0.43 0.11 0.07 0.27 0.41 0.521
IV) Oculomotor functions 3 0.46 0.007^b 0.57 0.048^a 0.30 0.03^a 0.49 0.18
6 0.04 0.37 0.05 0.42 0.17 0.10 0.24 0.046^a
a Significant with P < .05.
b Significance with P < .01.

Regression Type	SCA	Cerebellum		Brain Stem
Regression Type	SCA	Simple Ps.R²P	Including DD Ps.R²P	Simple Ps.R²P	Including DD Ps.R²P
I) Posture and gait	3	0.35 0.018^a	0.45 0.10	0.23 0.025^a	0.41 0.11
	6	0.41 0.010^a	0.43 0.062	0.23 0.044^a	0.36 0.10
II) Kinetic functions	3	0.05 0.32	0.065 0.72	0.14 0.14	0.14 0.19
	6	0.21 0.053	0.27 0.29	0.29 0.025^a	0.40 0.048^a
III) Speech functions	3	0.08 0.26	0.49 0.62	0.03 0.52	0.51 0.32
	6	0.30 0.036^a	0.43 0.11	0.07 0.27	0.41 0.521
IV) Oculomotor functions	3	0.46 0.007^b	0.57 0.048^a	0.30 0.03^a	0.49 0.18
	6	0.04 0.37	0.05 0.42	0.17 0.10	0.24 0.046^a