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Table 1: 
ROI and tract-based mean ADC and mean FA values of white matter pathways
CC PLIC CP LAF
ROI mean ADC × 10⁻³ mm²/s 
    Patients 1.11 ± 0.13 0.73 ± 0.02 0.88 ± 0.10 0.84 ± 0.07
    Controls 0.89 ± 0.03 0.70 ± 0.03 0.76 ± 0.05 0.76 ± 0.02
    P value 0.0020^a 0.021^a 0.020^a 0.0059^a
ROI mean FA 
    Patients 0.53 ± 0.06 0.62 ± 0.02 0.65 ± 0.06 0.39 ± 0.04
    Controls 0.63 ± 0.06 0.67 ± 0.03 0.69 ± 0.04 0.44 ± 0.02
    P value .0039^a .0039^a .13 .037^a
Tract mean ADC × 10⁻³ mm²/s 
    Patients 0.97 ± 0.10 0.76 ± 0.04 0.81 ± 0.06 0.85 ± 0.06
    Controls 0.86 ± 0.06 0.71 ± 0.03 0.73 ± 0.02 0.75 ± 0.02
     P value .037^a .0059^a .0020^a .0020^a
Tract mean FA 
    Patients 0.55 ± 0.06 0.56 v 0.03 0.58 ± 0.04 0.42 ± 0.04
    Controls 0.62 ± 0.03 0.59 ± 0.02 0.62 ± 0.03 0.48 ± 0.02
    P value .0098^a .0098^a .0039^a .0098^a

Note:—ROI indicates region of interest; CC, corpus callosum; PLIC, posterior limb of internal capsule; CP, cerebral peduncle; LAF, long association fibers; ADC, apparent diffusion coefficient; FA, fractional anisotropy.


a Statistically significant.