Table 2:

Summary of clusters in which ADC was found to be significantly reduced (P < .001) among patients compared with normal controls^a

MNI (x,y,z)	K	t	Controls		Patients		% Difference	Anatomical Locations	Side
MNI (x,y,z)	K	t	Mean	SD	Mean	SD	% Difference	Anatomical Locations	Side
b = 1000
(−12,−16,8)	20	4.96	777	45	684	63	12	Thalamus (medial dorsal nucleus, ventral lateral nucleus, ventral posterior lateral nucleus)	L
(10,−12,0)	30	4.90	769	40	683	60	11	Thalamus (medial dorsal nucleus, ventral lateral nucleus)	R
(18,12,−2)	6	4.47	782	68	670	76	14	Caudate body, caudate head, putamen	R
(24,4, −4)	31	4.24	725	46	613	80	15	Putamen	R
(16,10,10)	6	4.12	746	58	632	96	15	Caudate body	R
b = 2000
(16,−16,8)	121	6.37	722	40	624	70	13	Thalamus (medial dorsal nucleus, ventral lateral nucleus, ventral posterior lateral nucleus, pulvinar)	R
(26,6,2)	195	5.67	706	35	582	77	17	Caudate body, caudate head, putamen	R
(28,−14,2)	38	5.27	702	37	593	82	15	Putamen	R
(−6,−16,6)	43	5.05	700	35	607	67	13	Thalamus (medial dorsal nucleus, ventral lateral nucleus, ventral posterior lateral nucleus, ventral posterior medial nucleus)	L
(−16,−26,8)	6	4.27	737	59	641	80	13	Pulvinar	L
(−24,6,4)	20	3.87	712	40	585	123	18	Putamen	L

Note:—ADC indicates apparent diffusion coefficient; MNI (x,y,z), Montreal Neurological Institute coordinates of voxel at a peak t value; K, size of clusters in the unit of voxels; t, corresponding t value of a peak height.
^a Mean and SD were computed within each cluster. Percentage difference is defined by taking the ratio between mean ADC of patients and controls. The left and right hemisphere are identified as L and R.