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Table 2: Clinical and MRS data: changes with time (6 months)^a
ALS-L (n = 7) Baseline → Follow-Up ALS-B (n = 9) Baseline → Follow-Up PMA (n = 10) Baseline → Follow-Up Controls (n = 12) Baseline → Follow-Up
VC (%) 106.9 → 101.9 101.4 → 84.4^.013 101.0 → 91.3^.028 114.6 → 117.2
ALSFRS-R 42.6 → 39.3^.026 41.3 → 36.4^.011 41.8 → 36.8^.008 48.0 → 47.8
Finger tapping/s^b 3.32 → 2.49^.046 4.29 → 3.77^.038 4.83 → 4.28 5.10 → 4.98
Foot tapping/s^b 2.80 → 2.13 3.17 → 2.73 2.37 → 1.88 3.44 → 3.74
NAAx 8.79 → 9.07 8.65 → 8.21 9.72 → 9.18^.022 9.32 → 9.25
Glx 8.54 → 7.50 8.12 → 8.54 7.72 → 8.00 8.42 → 8.07
mIns 4.29 → 4.54 4.25 → 4.61 4.30 → 3.92 3.93 → 3.90
NAAx/mIns 2.11 → 2.04 2.08 → 1.86 2.37 → 2.39 2.45 → 2.40
a Values are means. P values (superscript) result from the Wilcoxon paired test for nonparametric data. Statistical significance was set at P < .05.
b Finger- and foot-tapping speed: (L + R) / 2.