Table 4:

Spearman rank correlation coefficients between the clinical-genetic variables and volumes and MT ratios in 15 HD carriers

	No. of Triplets		Disease Duration		Motor UHDRS		Verbal Fluency		Symbol Digit		Stroop
	R	P	R	P	R	P	R	P	R	P	R	P
Volumes
NWMV	0.46	NS	−0.22	NS	−0.44	NS	0.44	NS	0.65	<.01	0.54	.04
NGMV	−0.16	NS	−0.50	NS	−0.67	<.01	0.65	<.01	0.41	NS	0.40	NS
Frontal cortex	−0.40	NS	−0.60	.02	−0.59	.02	0.65	<.01	0.33	NS	0.31	NS
Parietal cortex	−0.38	NS	−0.67	<.01	−0.60	.02	0.74	<.01	0.37	NS	0.37	NS
Temporal cortex	−0.32	NS	−0.45	NS	−0.62	.01	0.60	.02	0.34	NS	0.45	NS
Occipital cortex	−0.07	NS	−0.36	NS	−0.66	<.01	0.77	<.001	0.61	.01	0.68	<.01
Caudate nuclei	−0.16	NS	−0.55	.03	−0.80	<.001	0.65	<.01	0.53	.04	0.46	NS
Putamen	−0.24	NS	−0.59	.02	−0.78	<.001	0.59	.02	0.50	NS	0.49	NS
Globi pallidi	−0.14	NS	−0.63	.01	−0.79	<.001	0.51	.0496	0.46	NS	0.37	NS
Thalami	−0.24	NS	−0.34	NS	−0.71	<.01	0.57	.03	0.51	NS	0.62	.01
MT ratios
WM	−0.14	NS	−0.72	<.01	−0.81	<.001	0.73	<.01	0.64	.01	0.64	.01
GM	−0.25	NS	−0.68	<.01	−0.81	<.001	0.88	<.0001	0.57	.04	0.58	.03
Frontal cortex	−0.34	NS	−0.65	<.01	−0.55	.03	0.61	.02	0.26	NS	0.23	NS
Parietal cortex	−0.26	NS	−0.66	<.01	−0.64	.01	0.63	.01	0.34	NS	0.30	NS
Temporal cortex	−0.05	NS	−0.77	<.001	−0.77	<.001	0.83	<.001	0.58	.02	0.49	NS
Occipital cortex	−0.36	NS	−0.61	.02	−0.71	<0.01	0.74	<.01	0.39	NS	0.41	NS
Caudate nuclei	0.02	NS	−0.60	.02	−0.23	NS	0.35	NS	0.21	NS	0.10	NS
Putamen	0.24	NS	−0.58	.02	−0.78	<.001	0.72	<.01	0.81	<.001	0.72	<.01
Globi pallidi	0.05	NS	−0.29	NS	0.55	.03	0.46	NS	0.51	NS	0.48	NS
Thalami	0.12	NS	−0.56	.03	−0.30	NS	0.30	NS	0.22	NS	0.09	NS

Note:—Bold indicates statistically significant data.