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Table 2: Sensitivity, specificity, and positive and negative predictive values of the germinal matrix, intermediate zone, subplate layer, and cortex on T1-weighted postmortem MRI
Sensitivity Specificity PPV NPV
T1 germinal matrix 80.00% 96.67% 95.24% 85.29%
(CI, 58.70%–92.39%) (CI, 80.95%–99.83%) (CI, 74.13%–99.75%) (CI, 68.17%–94.46%)
T1 intermediate zone 88.46% 89.66% 88.00% 89.66%
(CI, 68.72%–96.97%) (CI, 71.50%–97.29%) (CI, 68.72%–96.97%) (CI, 71.50%–97.29%)
T1 subplate layer 84.62% 93.10% 91.67% 87.10%
(CI, 64.27%–94.95%) (CI, 75.79%–98.80%) (CI, 71.53%–98.54%) (CI, 69.24%–95.78%)
T1 cortex 80.77% 100% 100% 85.29%
(CI, 60.02%–92.69%) (CI, 85.44%–100%) (CI, 80.76%–100%) (CI, 68.17%–94.46%)
T1 overall 96.15% 89.66% 89.29% 96.29%
(CI, 78.42%–99.80%) (CI, 71.50%–97.29%) (CI, 70.63%–97.19%) (CI, 79.11%–99.80%)