1naresh

Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1nareshArray
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)

Patient results
Patient 1 Patient 2 Patient 3 Patient 4
Age (y)/Sex 13/F 14/F 15/M 12/F
Symptoms 6 wk sore throat, odynophagia, voice change, neck mass 4 mos hoarseness, 1 mo odynophagia, dysphagia Nasal mass 3 wk URT symptoms and nasal mass
Tumor location Epiglottis Epiglottis and glottis Sinonasal Sinonasal
CT scan results 3-cm heterogeneously enhancing epiglottic mass necrotic, level II LN 3-cm heterogeneously enhancing submucosal mass 3 cm lobulated, moderately enhancing mass left nasal cavity, bony remodeling 5 × 7-cm moderately enhancing mass, nasal cavity. Bony destruction sinuses, skull base
MR imaging results Isointense with cortex on FSEIR Isointense with cortex on FSEIR Isointense with cortex on FSEIR
Surgery Modified radical neck dissection Biopsy Midface degloving; left Caldwell-Luc Biopsy
Histopathology Undifferentiated carcinoma Well-differentiated squamous carcinoma Poorly differentiated squamous carcinoma Poorly differentiated squamous carcinoma
Cytogenetics 47,XX, +8, t(15;19)(q13;p13.1). 46,XY, +der(1)t(1;5)(p12;q11.1), −5,del(22)(q11q13) T(15;19)
EBV Negative Negative Negative
Chemotherapy Cisplatin, 5-fluorouracil, docetaxel, methotrexate, vinblastine Cisplatin VCR/Cytoxan, Adriamycin, etoposide, carboplatin Carboplatin
Radiation 69 Gy to supraglottis 70.2 Gy to larynx 64.4 Gy to nasopharynx
54.0 Gy to neck nodes 52.2 Gy to neck nodes 50.4 Gy to neck nodes
Clinical course Disseminated disease. Death 10 mos after diagnosis Alive at 8 y f/u. Laryngeal scarring, stenosis. Tracheostomy Disease-free at 8 y f/u Disseminated disease. Death 3 mos VBIO, VCR after diagnosis