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Table 1: Summary of FA and MD (×10⁻³ mm²s⁻¹) values quantified in patients with PKAN, their siblings, and age-matched healthy controls in deep gray matter nuclei and ALIC
Subject CN Putamen GP SN ALIC
FA MD FA MD FA MD FA MD FA MD
Control (n = 5) 0.10 ± 0.01 0.76 ± 0.02 0.08 ± 0.01 0.70 ± 0.01 0.10 ± 0.01 0.70 ± 0.01 0.19 ± 0.01 0.69 ± 0.11 0.35 ± 0.01 0.71 ± 0.02
Sibling (n = 5) 0.10 ± 0.01 0.77 ± 0.02 0.08 ± 0.01 0.71 ± 0.01 0.11 ± 0.02 0.72 ± 0.02 0.22 ± 0.02 0.69 ± 0.12 0.35 ± 0.01 0.72 ± 0.01
Patient (n = 7) 0.10 ± 0.01 0.77 ± 0.03 0.08 ± 0.01 0.70 ± 0.02 0.18 ± 0.03 0.75 ± 0.06 0.32 ± 0.02 0.67 ± 0.10 0.36 ± 0.01 0.71 ± 0.03
P value^a .17 .23 .31 .10 <.001 <.001 <.001 .71 .83 .16
a ANOVA.

Subject	CN		Putamen		GP		SN		ALIC
Subject	FA	MD	FA	MD	FA	MD	FA	MD	FA	MD
Control (n = 5)	0.10 ± 0.01	0.76 ± 0.02	0.08 ± 0.01	0.70 ± 0.01	0.10 ± 0.01	0.70 ± 0.01	0.19 ± 0.01	0.69 ± 0.11	0.35 ± 0.01	0.71 ± 0.02
Sibling (n = 5)	0.10 ± 0.01	0.77 ± 0.02	0.08 ± 0.01	0.71 ± 0.01	0.11 ± 0.02	0.72 ± 0.02	0.22 ± 0.02	0.69 ± 0.12	0.35 ± 0.01	0.72 ± 0.01
Patient (n = 7)	0.10 ± 0.01	0.77 ± 0.03	0.08 ± 0.01	0.70 ± 0.02	0.18 ± 0.03	0.75 ± 0.06	0.32 ± 0.02	0.67 ± 0.10	0.36 ± 0.01	0.71 ± 0.03
P value^a	.17	.23	.31	.10	<.001	<.001	<.001	.71	.83	.16