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Table 1: Mean (± SD) global and regional CC measures for patients with NF-1 and matched controls^a
Patients with NF-1 (n= 10) Matched Controls (n= 10) t Statistic (df = 9)
Global CC measures 
    Central length (mm) 94.1 (5.7) 85.4 (5.7) 3.46^b
    Area (mm²) 708.4 (74.9) 587.2 (53.8) 4.15^b
    Total brain volume (cm³) 1050 (110) 1010 (90) 0.89
Factor groupings (mm) 
    F1 (widths 3–18) 13.0 (3.2) 14.5 (1.6) 1.33
    F2 (widths 22–39) 9.2 (1.7) 7.3 (0.7) 3.21^b
    F3 (widths 49–62) 7.9 (1.4) 6.6 (0.7) 2.58^c
    F4 (widths 65–74) 7.9 (0.8) 6.2 (0.7) 5.09^b
    F5 (widths 77–85) 12.7 (1.9) 10.8 (1.2) 2.67^c
    F6 (widths 89–94) 14.3 (1.7) 13.2 (1.9) 1.40
    F7 (widths 95–99) 5.1 (0.4) 4.6 (0.3) 2.55^c


a There is no significant difference between the total brain volumes of the subjects with NF-1 and controls, but the area and length of the CC are larger in NF-1. The factor groupings are also presented pictorially in Fig 1.


b P <.05 after the Bonferroni correction.


c P < .05 before the Bonferroni correction (.05/10) only.