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Patient demographic and clinical information
Patient No. Sex Age (yr) Diagnosis Tumor Location Treatment Prior to RT (Time of Administration before RT, mo)a Radiation Dose (Gy) Anterior Posterior Surgery Chemotherapy Steroids I-V VI-VII VIII-X 1 M 5.5 Pilocytic astrocytoma Right frontal suprasellar/optic Yes (42.7) CaPt (35.0), TMZ (16.5) No 18.5 20.4 23.5 2b F 8.5 Anaplastic medulloblastoma Posterior fossa Yes (5.8) CsPt/VP-16/ CTX/VCR/MTX (5.2) Dex (5.3) 54.4 54.3 54.3 3 F 8.7 Nonanaplastic medulloblastoma Posterior fossa Yes (1.1) No Dex (0.8) 54.0 54.0 54.0 4b M 9.2 Anaplastic medulloblastoma Fourth ventricle Yes (1.5) No Dex (1.5) 54.5 54.5 54.5 5 M 10.2 T-cell ALL No tumor No T-cell IC (1.1) Pred (0.7) 18.3 18.3 18.3 6 M 11.8 Nondiagnostic biopsy (astrocytoma or ependymoma) Pineal No (VP shunt) No No 14.9 4.8 30.0 7 M 11.8 Malignant glioneuronal tumor, otherwise unclassifiable Left frontal Yes (5.7) No No 41.4 41.0 34.5 8 M 15.3 Ependymoma Left medial temporal lobe Yes (0.9) No No 36.7 36. 8 38.0 9b M 16.0 Pontine glioma Pons No No Dex (2.0) 50.6 24.7 33.1 10 F 18.6 Germinoma Suprasellar Yes (4.1) CsPt/VP-16/ CTX/VCR/(3.1) HC (3.7) 20.3 15.4 16.0
Note:—In all patients with medulloblastoma, the posterior vermis was affected by surgery. None of the patients were diagnosed with obstructive hydrocephalus; moderately enlarged ventricles were noted in patients 1 and 6. Postsurgical mutism was diagnosed in patient 3.
a Time of administration before the start of radiation treatment is shown.
b Patient died.