1naresh
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Aphasia Improvement (n = 21) No Improvement (n = 37) P Value Age 69.5 ± 3.8 76.8 ± 1.9 .10 Female 11 (52%) 21 (57%) .78 Admission NIHSS score 8 (2–23) 19 (5–28) .001a Admission aphasia NIHSS score 2 (1–3) 3 (1–3) .002a Major proximal arterial occlusion 7 (33%) 30 (81%) .001a Thrombolytic therapy (IV) 5 (24%) 11 (29%) .76 IA thrombectomyb 1 (5%) 3 (8%) 1.00 Ictus to IV treatment interval (hour) 2.11 ± 0.25 1.93 ± 0.25 .67 IV treatment to CTP interval (hour)c 1.13 ± 0.49 1.51 ± 0.52 .68 Ictus to CTP interval (hour) 4.46 ± 0.57 4.78 ± 0.48 .68
a Significant.
b Of the 4 patients who received thrombectomy, only 1, who had complete recanalization, subsequently showed language improvement. All patients who received thrombectomy had first received IV thrombolysis.
c Only 1 patient with and 4 without language improvement received IV thrombolysis following CTP; negative treatment-to-CTP-time values were calculated for these patients.