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Table 1:

Comparison of clinical/CTA characteristics between patients with and without improvement of aphasia (univariate analysis)

Aphasia Improvement (n = 21)No Improvement (n = 37)P Value
Age69.5 ± 3.876.8 ± 1.9.10
Female11 (52%)21 (57%).78
Admission NIHSS score8 (2–23)19 (5–28).001a
Admission aphasia NIHSS score2 (1–3)3 (1–3).002a
Major proximal arterial occlusion7 (33%)30 (81%).001a
Thrombolytic therapy (IV)5 (24%)11 (29%).76
IA thrombectomyb1 (5%)3 (8%)1.00
Ictus to IV treatment interval (hour)2.11 ± 0.251.93 ± 0.25.67
IV treatment to CTP interval (hour)c1.13 ± 0.491.51 ± 0.52.68
Ictus to CTP interval (hour)4.46 ± 0.574.78 ± 0.48.68
  • a Significant.

  • b Of the 4 patients who received thrombectomy, only 1, who had complete recanalization, subsequently showed language improvement. All patients who received thrombectomy had first received IV thrombolysis.

  • c Only 1 patient with and 4 without language improvement received IV thrombolysis following CTP; negative treatment-to-CTP-time values were calculated for these patients.