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TABLE Results of AVM embolization with 2-P-HEMA and evaluation of its properties
 Animal Patent AVM 2-P-HEMA Concentration Injection Location and Volume (mL) Injection Speed (mL/mim) Occlusion of Embolized Nidus Compartment Complications Detected at Angiography Postembolization MR Imaging and CT Finding Time of Follow-Up Angiography and Nidus Occlusion
1 Yes Pure PA, 0.6; RA, 0.4 0.1 PA complete, RA complete None Partial infarction in right hemisphere, no 2-P-HEMA in brain vessels At 1 and 8 mo: PA complete, RA complete
2 Yes Pure PA, 0.4 0.4 PA complete Vasospasm Normal At 3 mo: complete; at 5 mo: partial recanalization
3 Yes Pure PA, 0.7; RA, 0.4 0.1 PA complete, RA complete None Normal At 2 and 7 mo: PA complete, RA complete
4 Yes Pure PA, 0.6 0.1 PA complete None Normal At 1 and 6 mo: complete
5 Yes Pure PA, 0.5 0.1 PA complete None Normal At 2 and 6 mo: complete
6 Yes Pure PA, 0.8 0.1 PA complete None Normal At 1 and 8 mo: complete
7 Yes 50% PA. 0.6 0.1 PA incomplete Embolic events Infarction in right hemisphere, 2-P-HEMA in brain vessels At 15 h: incomplete
* To make pure 2-P-HEMA, 11% 2-P-HEMA by volume was dissolved in 89% ethenol by volume. To make 50% 2-P-HEMA, 5.5% 2-P-HEMA by volume was dissolved in 79.5% ethanbol boy volume. Sterilized 2-P-HEMA (1 mL) was mixed with tungsten (0.005 g).