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TABLE 1: 
Demographic, clinical, and MR imaging characteristics of patients with different multiple sclerosis phenotypes
RRMSSPMSPPMS
Mean age in years (SD)34.8 (7.5)47.8 (9.1)50.8 (7.5)
Mean disease duration in years (range)6.5 (2–17)15.5 (3–34)10.0 (2–20)
Median EDSS score (range)1.5 (1.0–4.5)6.0 (3.5–7.5)6.0 (3.0–8.5)
Median T2 lesion load in milliliters (range)12.2 (0.4–38.2)31.2 (6.1–87.7)15.1 (1.7–65.0)
Mean brain volume in milliliters (SD)1137 (98)1074 (91)1116 (108)
  • Note.—RRMS indicates relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; PPMS, primary progressive multiple sclerosis; EDSS, Expanded Disability Status Scale.