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TABLE 1: Differences in slopes between patients who received reduced (23.4 Gy) or conventional (36–39.6 Gy) craniospinal irradiation doses
CC Region CSI Dose (Gy) Slope^* Significance^{^†}
Total Reduced −20.0 0.52
Conventional −16.0 
Rostrum Reduced 0.2 0.29
Conventional 1.4 
Genu Reduced −0.1 0.20
Conventional −4.6 
Rostral body Reduced −2.4 0.55
Conventional −1.2 
Anterior midbody Reduced −1.6 0.81
Conventional −1.2 
Posterior midbody Reduced −1.4 0.98
Conventional −1.4 
Isthmus Reduced −2.0 0.75
Conventional −2.2 
Splenium Reduced −7.0 0.17
Conventional −2.4 
Note.—CC indicates corpus callosum; CSI, craniospinal irradiation.
* Change in CC size per year since start of CSI (mm²).
† Testing H₀: slope (reduced) = slope (conventional); P < .05, two-tailed test.

CC Region	CSI Dose (Gy)	Slope^*	Significance^{^†}
Total	Reduced	−20.0	0.52
	Conventional	−16.0
Rostrum	Reduced	0.2	0.29
	Conventional	1.4
Genu	Reduced	−0.1	0.20
	Conventional	−4.6
Rostral body	Reduced	−2.4	0.55
	Conventional	−1.2
Anterior midbody	Reduced	−1.6	0.81
	Conventional	−1.2
Posterior midbody	Reduced	−1.4	0.98
	Conventional	−1.4
Isthmus	Reduced	−2.0	0.75
	Conventional	−2.2
Splenium	Reduced	−7.0	0.17
	Conventional	−2.4