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TABLE 2: NAA/(Cr + Cho) in patients and control subjects in the hippocampus versus other brain regions
Brain Region Controls Temporal Lobe Epilepsy
Ipsilateral^* Contralateral^†
Hippocampus (PRESS) 1.27 ± 0.19 1.10 ± 0.15 (P < .01) 1.20 ± 0.16 (P < .05)
Hippocampal body (multisection MRS) 1.34 ± 0.23 1.09 ± 0.21 (P < .01) 1.30 ± 0.24 (P < .0001)
Temporal operculum (multisection (MRS) 1.50 ± 0.16 1.20 ± 0.22 (P < .001) 1.46 ± 0.18 (P < .001)
Insular cortex (multisection MRS) 1.44 ± 0.13 1.17 ± 0.18 (P < .001) 1.43 ± 0.21 (P < .001)
Lateral temporal cortex (multisection MRS) 1.69 ± 0.16 1.36 ± 0.35 (P < .05) 1.76 ± 0.25 (P < .05)
Cerebellar hemisphere (multisection MRS) 1.33 ± 0.19 1.34 ± 0.19 (N.S.) 1.33 ± 0.18 (N.S.)
Cerebral hemisphere (multisection MRS) 1.99 ± 0.14 1.85 ± 0.10 (P < .01) 1.92 ± 0.08 (P < .001)
Note.—All values are expressed in institutional units as mean ± SD.
* P values reflect significantly reduced ratios in patients compared with ratios in control subjects.
† P values reflect significantly reduced ratios in the ipsilateral side compared with ratios in the contralateral side of patients.