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TABLE 2: Averaged ADC and FA values for the control subjects and patients
A: ADC values, mm²/sec
ROI Control Subjects, × 10⁻⁶ Patients, ×10⁻⁶ P Value
Internal capsule 674 ± 81 683 ± 59 .732
Splenium^* 769 ± 61 628 ± 74 .001
Thalamus 718 ± 60 719 ± 62 .975
Putamen 677 ± 75 707 ± 55 .184
B: FA values
ROI Control Subjects Patients P Value
Internal capsule^* 0.725 ± 0.066 0.624 ± 0.072 <.001
Splenium^* 0.808 ± 0.060 0.678 ± 0.010 .002
Thalamus 0.377 ± 0.075 0.401 ± 0.040 .147
Putamen 0.286 ± 0.081 0.307 ± 0.040 .257
Note.—Table lists the mean ADC and FA values ± SD for all patients and control subjects within the respective ROIs. Left- and right-sided ADC and FA values were averaged. A statistically significant ADC decrease is seen for the splenium, and a statistically significant FA decrease is seen for the internal capsule. A P value of <.005 was considered to indicate a statistically significant difference. Analysis was performed by using a two-tailed Wilcoxon rank sum test.
* Statistically significant difference.