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TABLE 3: PCT rCBV values for the healthy hemisphere
Group Sampling Interval
0.5 second 1 second^* 2 seconds 3 seconds 4 seconds 5 seconds 6 seconds
1 (30 mL) 
 Mean ± SD 3.0 ± 0.4 2.8 ± 0.5 2.9 ± 0.4 3.0 ± 0.5 3.9 ± 0.7 4.8 ± 1.3 14.9 ± 4.8
 Range −6.5% to +8.0% NA −7.5% to +6.8% −6.2% to +9.2% +16.8% to +59.4% +52.5% to +99.1% +136.0% to +628.3%
 P value .213 NA .700 .124 .004 .002 <.001
2 (40 mL) 
 Mean ± SD 3.1 ± 0.5 3.0 ± 0.4 2.8 ± 0.4 3.2 ± 0.5 3.2 ± 0.6 4.3 ± 0.7 4.9 ± 1.2
 Range −5.8% to +7.1% NA −8.3% to +4.9% −5.8% to +7.4% −4.2% to +9.6% +18.0% to +69.3% +42.0% to +278.2%
 P value .225 NA .595 .0196 .024 <.001 <.001
3 (50 mL) 
 Mean ± SD 3.2 ± 0.4 3.1 ± 0.5 2.9 ± 0.4 3.0 ± 0.3 3.3 ± 0.5 3.9 ± 0.6 4.1 ± 0.8
 Range −7.2% to +6.2% NA −9.0% to +7.9% −7.4% to +8.3% −5.3% to +8.3% +7.9% to +41.6% +22.3% to +66.6%
 P value .708 NA .243 .494 .139 .008 .007
4 (60 mL) 
 Mean ± SD 3.2 ± 0.4 3.1 ± 0.5 2.9 ± 0.4 2.9 ± 0.3 3.2 ± 0.4 3.3 ± 0.4 3.7 ± 0.5
 Range −6.5% to +8.0% NA −8.3% to +10.2% −8.1% to +9.0% −5.8% to +7.6% −4.8% to +9.6% +8.5% to +32.6%
 P value .230 NA .650 .420 .324 .038 .007
Note.—No significant difference (P = .908, Kruskal-Wallis) was identified among the four groups for rCBV values obtained with an interval of 1 second. Range indicates the overestimation or underestimation compared with the reference. Values in boldface indicate the temporal sampling interval thresholds beyond which rCBV values were significantly overestimated.
* Reference for Wilcoxon (Mann-Whitney) tests performed in each group. NA indicates not applicable.