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TABLE 1: 
Pressure and flow in the dome of a surgically created canine aneurysm, injection at 15 mL/s over 2 seconds
CharacteristicBefore GDC PlacementAfter GDC Placement
In VivoIn VitroP ValueIn VivoIn VitroP Value
Increase in pressure P43.2 ± 8.684.2 ± 4.5<.0589.2 ± 9.0*55.8 ± 3.2*<.05
Change in temperature ΔT, °C11.48 ± 1.1111.55 ± 0.40>.052.89 ± 1.89*4.34 ± 1.35*>.05
Pressure-flow shift ε, seconds0.31 ± 0.040.26 ± 0.08>.051.07 ± 0.52*0.46 ± 0.12<.05
Dilution interval, seconds6.60 ± 2.446.98 ± 1.21>.0526.98 ± 9.74*25.7 ± 12.65*>.05
  • Note.—Injections were normal saline at room temperature. Data are the mean ± SD. P values were determined with a two-sided Student t test.
  • * P <.05 before GDC placement versus after GDC placement.