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TABLE 2: ADC values in three patients with PBD and age-matched controls
ADC values × 10⁻³ mm²/s N 12 Months 16 Months 80 Months
Patient Control Diff. % Patient Control Diff. % Patient Control Diff. %
Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Genu of corpus callosum 12 111 (7) 107 (9) 4 4 98 (8) 75 (9) 22 30^‡ 92 (10) 69 (5) 24 35^‡
Splenium of corpus callosum 12 115 (12) 122 (23) −7 −6 98 (9) 83 (7) 15 18^‡ 110 (10) 88 (16) 22 25^‡
Parietal corona radiata R 51 131 (7) 106 (8) 25 24^‡ 117 (5) 102 (8) 15 15^‡ 102 (7) 93 (15) 8 9^‡
L 51 137 (5) 108 (6) 30 28^‡ 129 (7) 109 (4) 20 19^‡ 94 (8) 91 (6) 2 3^*
Frontal corona radiata R 51 127 (4) 105 (6) 23 22^‡ 115 (6) 91 (5) 24 27^‡ 94 (5) 73 (5) 20 28^‡
L 51 124 (5) 110 (11) 14 13^‡ 114 (5) 94 (4) 21 22^‡ 92 (5) 84 (5) 8 10^‡
Centrum semiovale R 51 131 (6) 95 (3) 35 37^‡ 106 (5) 100 (5) 6 6^‡ 100 (9) 84 (6) 16 20^‡
L 51 141 (4) 94 (5) 47 49^‡ 110 (4) 99 (5) 11 11^‡ 95 (5) 91 (9) 4 4^†
Note.—N indicates number of pixels per region of interest; significance determined with t test:
* P < .05;
† P < .01;
‡ P < .001.