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TABLE 1: Distribution of MR Imaging Parameters during the Acute Phase of Ischemic Stroke
MR Imaging Parameter (No. of Tissues) Total n = 200 (%) rt-PA Treatment n = 49 (%) No rt-PA Treatment n = 151 (%) P Value^*
Signature number 
    <3 43 (21.5) 10 (4.5) 33 (17.0) 
    4 71 (35.5) 21 (10.5) 50 (25.0) 
    5 57 (28.5) 10 (5) 47 (23.5) 
    ≥6 29 (14.5) 8 (4) 21 (13.82) 0.49
rADC 
    Median 0.78 0.79 0.77 0.91
    (2^nd, 3^rd QL) (0.66, 0.91) (0.68, 0.90) (0.65, 0.92) 
rT2 
    Median 18 1.19 1.17 0.20
    (2^nd, 3^rd QL) (1.09, 1.33) (1.10, 1.34) (1.10, 1.25) 
ADC 
    Median 609.8 μm²/s 620.4 μm²/s 608.3 μm²/s 0.79
    (2^nd, 3^rd QL) (513.8, 694.6) (548.5, 675.4) (497.1, 707.5) 
T2 
    Median 85.1 81.0 86.2 0.04
    (2^nd, 3^rd QL) (78.0, 97.6) (76.7, 89.3) (78.1, 98.9) 
Stroke onset to MR imaging time 
    Median 9.4 7.9 9.8 0.24
    (2^nd, 3^rd QL) (7.8, 11.8) (5.6, 12.0) (8.8, 11.0) 
Note.—rt-PA indicates recombinant tissue plasminogen activator; rADC, relative apparent diffusion coefficient; rT2, relative T2; QL, quartile; ADC, apparent diffusion coefficient.
* Comparison between rt-PA-treated and non-rt-PA-treated groups using the generalized estimation equations approach considering the correlation among sections and among tissues.