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Subject demographics, CAG repeat size, and test scores

MeasureParticipants
FarCloseControl
Age (years)*33.0 (5.0)41.1 (5.9)38.0 (6.1)
Education (years)14.6 (2.4)14.1 (1.7)14.9 (1.9)
Sex (M/F)(2/5)(4/3)(2/5)
CAG repeat size41.3 (2.1)44.2 (2.5)NA
Estimated years to symptom onset24.6 (7.9)8.6 (2.5)NA
UHDRS motor score0.7 (1.0)1.4 (0.9)NA
UHDRS verbal fluency39.9 (11.7)32.9 (8.7)39.4 (6.4)
UHDRS symbol-digit57.3 (10.0)44.9 (8.8)52.4 (10.9)
UHDRS stroop interference50.9 (13.1)37.1 (12.2)44.0 (7.5)
  • Note.—NA indicates not applicable; UHDRS, Unified HD Rating Scale. Data are the mean (standard deviation).

  • * Close participants were significantly older than far participants (P < .05).

  • Close participants had a significantly longer CAG repeat size than that of far participants (P < .05).

  • In the close group, onset was predicted significantly earlier than in the far group (P < .001).