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TABLE 3: Comparison of T1 metrics between control participants and patients with multiple sclerosis
White Matter Gray Matter Relative Height Relative Distance
Position Width Position Width
Control participants 667 70 1077 233 2.26 409
All patients with MS 722 83 1090 207 2.05 367
P values <0.001 <0.001 0.33 <0.001 0.003 <0.001
RRMS and SPMS 714 79 1088 212 2.02 373
P values <0.001 0.001 0.38 0.002 0.002 <0.001
Note.—The two-tailed Student’s t test with unequal variance is used to derive statistical significances (P values). MS, multiple sclerosis; RRMS, relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis.

	White Matter		Gray Matter		Relative Height	Relative Distance
	Position	Width	Position	Width	Relative Height	Relative Distance
Control participants	667	70	1077	233	2.26	409
All patients with MS	722	83	1090	207	2.05	367
P values	<0.001	<0.001	0.33	<0.001	0.003	<0.001
RRMS and SPMS	714	79	1088	212	2.02	373
P values	<0.001	0.001	0.38	0.002	0.002	<0.001