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Summary of clinical and imaging findings
Case Patient Age/Sex Signs of Edema^* Attenuation Value (HU)^† Proof^‡ Diagnosis at Death or Discharge^§
1 5 y/M C, E NA Autopsy result Diffuse cerebral edema secondary to hyponatremia
2 37 y/F C, E, GW NA Autopsy result Sudden cardiac death, anoxic injury
3 22 y/M C, E NA Negative LP result Pseudo-tumor cerebri
4 22 y/F C, E NA Autopsy result DKA with hypoxic and metabolic encephalopathy
5 8 mo/F E, GW 29 Negative LP result Diffuse cerebral edema, SIDS
6 5 y/M C, E, GW 33 Negative LP result Cardiopulmonary failure secondary to unknown metabolic disorder (possibly Leigh disease)
7 6 y/M C, E, GW 29 Negative LP result Septic Shock
* C indicates compression and/or mass effect on the fourth ventricle; E, effacement of the basal cisterns and cortical sulci; GW, decreased gray matter–white matter differentiation.
† Mean attenuation levels were obtained with a region of interest drawn in the basal cisterns. NA indicates not available.
‡ LP indicates lumbar puncture.
§ DKA indicates diabetic ketoacidosis; SIDS, sudden infant death syndrome.