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TABLE 4: Differentiation of histologic tumor types
Parameter HGA (n = 8) MET (n = 8) LGA (n = 12) NAG (n = 8) MNG (n = 7) DNET (n = 3)* GRN (n = 3)* F Score† P Value† Mean SD Mean SD Mean SD Mean SD Mean SD Mean SD Mean SD NAA/Cho 0.55 0.36 0.74 0.20 0.67 0.25 0.64 0.31 0.85 0.35 1.98 0.23 0.90 0.49 1.105 NS‡ NAA/Cr 0.96 0.40 1.11 0.31 1.04 0.44 1.08 0.41 1.42 0.61 1.71 0.26 1.14 0.37 1.240 NS‡ NAA/Cho + Cr 0.34 0.18 0.44 0.11 0.40 0.14 0.39 0.14 0.52 0.20 0.92 0.12 0.50 0.22 1.364 NS‡ Cho/Cr 2.05 0.85 1.53 0.35 1.61 0.45 1.85 0.70 1.76 0.74 0.86 0.05 1.35 0.26 0.910 NS‡ Lipid/Cr 0.22 0.14 0.76 0.25 0.19 0.10 0.33 0.21 0.37 0.22 0.25 0.06 0.13 0.03 13.210 .000§ Lactate/Cr 0.27 0.26 0.44 0.11 0.16 0.19 0.32 0.25 0.00 0.00 0.00 0.00 0.00 0.00 3.691 .012| Lactate/lipid 1.27 1.12 0.60 0.11 0.78 0.85 0.79 0.60 0.33 0.56 0.00 0.00 0.00 0.00 1.619 NS Alanin/Cr 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.39 0.21 0.00 0.00 0.00 0.00 32.104 .000¶ ADCT 89.44 12.98 84.88 7.22 112.58 9.44 119.44 14.05 107.14 8.03 116.00 6.93 100.67 17.74 16.537 .000# ADCPT 128.44 26.83 168.69 19.86 169.63 40.59 163.50 17.56 101.29 39.41 91.50 7.12 80.50 7.09 7.416 .000**
Note.—HGA indicates high-grade glioma; MET, metastasis; LGA, low-grade glioma; NAG, nonastrocytic gliomas; MNG, meningioma; DNET, dysembryoplastic neuroepithelial tumor; GRN, granuloma; ADCT, calculated ADC values from tumoral area; ADCPT, calculated ADC values from peritumoral area; NS, not significance.
* DNET and GRN were excluded from statistical comparison because of their low sample number.
† F score and P values were obtained by using Tukey pairwise post hoc test.
‡ Although the omnibus test was statistically significant, none of the pairwise post hoc tests reached significance.
§ MET > HGA, MET > LGA, MET > NAG P < .001; MET > MNG P < .05; otherwise NS.
| MET > LGA, MET > MNG P < .05; otherwise NS.
¶ MNG > HGA, MNG > MET, MNG > LGA, MNG > NAG P < .001; otherwise NS.
# LGA > HGA, LGA > MET, NAG > HGA, NAG > MET P < .001; MNG > HGA, MNG > MET P < .05; otherwise NS.
** LGA > MNG P < .001; LGA > HGA, MET > MNG, NAG > MNG P < .05; otherwise NS.