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          TABLE 1:
         
            Clinical characteristics, neuropsychiatric symptoms, and radiologic abnormalities of 11 patients with a history of NPSLE
          
Patient No./Age/Sex MR Imaging Abnormalities Mean WML size, mm NP Symptoms and Time Since Occurrence^*
1/47 y/F 2 WMLs 5 ±0 Cerebrovascular disease,^† 3 mo
2/6 mo/F Small cerebellar infarction, cerebral atrophy, 2 WMLs 6 ± 1.4 Primary generalized tonic-clonic seizures, 6 mo
3/41 y/F 7 WMLs 3.7 ± 2.0 Movement disorder, 18 mo
4/25 y/F 6 WMLs, cerebral atrophy 3.7 ± 1.0 Absence seizures, 10 mo
5/27 y/F No WML NA Cerebrovascular disease,^† 10 mo
6/36 y/F No WML NA Cerebrovascular Disease,^† 6 mo
7/49 y/F 21 WML 3.0 ± 1.1 Cranial neuropathy, 2 mo
8/32 y/F Cerebral trophy, 29 WMLs 6.3 ± 3.9 Cerebrovascular disease,^† cognitive dysfunction, 5 mo
9/26 y/F No WML NA Acute confusional state, 10 mo
10/24 y/F Small venous angioma, left frontal NA Absence seizures, 7 mo
11/39 y/F No WML NA Headache from intracranial hypertension, 5 mo
Note.—WML indicates white matter lesion.
* According to the American College of Rheumatology nomenclature and case definitions for NPSLE.
† No infarctions present on MR images obtained at the time of manifestation.