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TABLE 1: 
Clinical findings for 54 children with hippocampal sclerosis, with and without anterior temporal changes
Clinical Finding n=54AT Signal Changes n = 31No AT Signal Changes n=23
Mean age at onset of epilepsy (years ±SD)4.3 (±2.8)6.7 (±3.6)P < .01
Age at previous cerebral insult (years ±SD)0.9 (±0.7)3.2 (±3.6)P < .03
Duration of epilepsy (years ±SD)*6.9 (±4.1)4.4 (±4.5)P < .04
Mean number of seizures (±SD)*1730 (±3730)325 (±480)P < .05
Number treated surgically (%)*19 (61%)5 (22%)P < .004
Mean age at time of MR imaging (years ±SD)11.2 (±4.2)11.4 (±4.6)ns
Gender (male:female)15:168:15ns
Number with previous cerebral insult2717ns
Time from insult to epilepsy onset (years ±SD)3.1 (±2.8)3.9 (±3.5)ns
Overall seizure frequency (sz/wk ±SD)7 (±15.8)3 (±6.2)ns
Seizure frequency before MR imaging (sz/wk ±SD)4.6 (±7.6)4.4 (±8.7)ns
Number with previous febrile convulsions (%)15 (48%)9 (39%)ns
Number with family history of epilepsy (%)10 (32%)7 (30%)ns
  • Note.—AT indicates anterior temporal; sz, seizures; wk, week; ns, not significant.
  • * Dependent on the age at onset of epilepsy.