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Patients with NF1
Location No. of Patients (n=31)
Soft-tissue tumor without orbital involvement 7 (22.6)
Radiologic orbital changes 24 (77.4)
Distortion due to an enlarged middle cranial fossa 13 (41.9)
Orbital-rim enlargement 18 (58.1)
 Associated with buphthalmos 13
 Associated with a small maxillary sinus 13
 Associated with tumor in the anterior orbit 2
Imaging evidence of tumor within the orbit 19 (61.3)
 Intraconal tumor 13
 Globe (buphthalmos with or without enucleation) 13
 Lacrimal gland 11
 Extraocular muscle 13
 Posterior orbit 16
 Orbital bone 18
Expansion of the orbital foramen 16 (51.6)
 Expansion of the superior orbital fissure 15
 Expansion of the inferior orbital fissure 12
 Expansion of the optic canal 8
  Optic nerve glioma only 6
  PNF infiltration of the optic nerve sheath 2
Note.—Data in parentheses are percentages.

Location	No. of Patients (n=31)
Soft-tissue tumor without orbital involvement	7 (22.6)
Radiologic orbital changes	24 (77.4)
Distortion due to an enlarged middle cranial fossa	13 (41.9)
Orbital-rim enlargement	18 (58.1)
Associated with buphthalmos	13
Associated with a small maxillary sinus	13
Associated with tumor in the anterior orbit	2
Imaging evidence of tumor within the orbit	19 (61.3)
Intraconal tumor	13
Globe (buphthalmos with or without enucleation)	13
Lacrimal gland	11
Extraocular muscle	13
Posterior orbit	16
Orbital bone	18
Expansion of the orbital foramen	16 (51.6)
Expansion of the superior orbital fissure	15
Expansion of the inferior orbital fissure	12
Expansion of the optic canal	8
Optic nerve glioma only	6
PNF infiltration of the optic nerve sheath	2