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TABLE 1: 
Grading of white matter abnormalities based on ultrasonography and MR imaging
Description of White Matter Abnormalities
Ultrasonography
 Grade 1Small foci of abnormal echogenicity less echogenic than choroid plexus
 Grade 2Diffuse foci of increased echogenicity less than the choroid plexus or irregularity of the lateral borders of the periventricular white matter (junction of the normal halo and surrounding cortex)
 Grade 3Focal areas of abnormal echogenicity greater than or equal to the echogenicity of the choroid plexus
 Grade 4Diffuse increased echogenicity greater than or equal to the echogenicity of the choroid plexus
 Grade 5Periventricular cysts (cavitation) defined as anechoic regions with increased through transmission
 MR imaging
  NormalNo periventricular white matter abnormalities
  Minimal white matter abnormalityThree or fewer areas of T1 signal abnormalities measuring <2 mm
  Moderate white matter abnormalityThree areas of T1 signal abnormalities or areas measuring >2 mm but <5% of the hemisphere involved*
  Severe white matter abnormalityT1 signal abnormalities involving >5% of the hemisphere
  • * Percent of hemisphere involved estimated by visual inspection.