1naresh
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Metabolite Controls (n = 15) ALS-All (n = 24) El Escorial Criteria ALS-FTD (n = 2) Possible (n = 5) Probable (n = 15) Definite (n = 4) NAA/mIns 1.95 ± 0.27 1.62 ± 0.31 1.65 ± 0.23 1.63 ± 0.37 1.53 ± 0.10 1.10 ± 0.19 NAA (mmol/L) 9.82 ± 1.76 8.92 ± 1.29 9.22 ± 0.65 8.77 ± 1.36 9.14 ± 1.80 7.02 ± 2.02 mIns (mmol/L) 5.06 ± 0.76 5.63 ± 0.96 5.67 ± 0.89 5.06 ± 0.75 5.99 ± 1.14 6.34 ± 0.71
Note:—Spectroscopy quantities are mean ± SD. Patients are categorized according to disease stage by El Escorial Criteria or presence of dementia (ALS-FTD).