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Table 2: 
HRs with 95% CIs comparing risk of death after adjusting for age in treated-versus-untreated cohorts
Subgroup HR (95% CI)
All subjects: treated-vs-untreated cohort 
    Univariate 1.62 (1.35–1.96)
    Sex adjustment 1.41 (1.17–1.71)
    Sex + Charlson score adjustment 1.17 (0.96–1.42)
Charlson index = 0 
    Univariate 1.50 (0.86–2.61)
    Sex adjustment 1.46 (0.84–2.55)
Charlson index = 1–3 
    Univariate 1.09 (0.83–1.43)
    Sex adjustment 1.00 (0.76–1.32)
    Sex + Charlson score adjustment 0.94 (0.71–1.24)
Charlson index >3 
    Univariate 1.35 (0.99–1.83)
    Sex adjustment 1.26 (0.91–1.73)
    Sex + Charlson score adjustment 1.20 (0.87–1.66)
All subjects: treated vs symptomatic untreated cohort 
    Univariate 1.32 (1.08–1.62)
    Sex adjustment 1.20 (0.98–1.48)
    Sex + Charlson score adjustment 1.02 (0.82–1.25)
Charlson index = 0 
    Univariate 1.22 (0.68–2.19)
    Sex adjustment 1.22 (0.68–2.19)
Charlson index = 1–3 
    Univariate 0.97 (0.72–1.30)
    Sex adjustment 0.92 (0.68–1.24)
    Sex + Charlson score adjustment 0.86 (0.64–1.16)
Charlson index >3 
    Univariate 1.07 (0.76–1.51)
    Sex adjustment 1.02 (0.72–1.45)
    Sex + Charlson score adjustment 1.00 (0.71–1.42)