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Table 1: Demographic and endocrine data^a
Lean Obese P
Sample size 31 48 –
Female 55% (17) 69% (33) .21
Age (yr) 17.1 ± 1.6 17.9 ± 1.5 .018
SES category^b 2.5 ± 1.5 2.0 ± 1.1 .154
BMI (kg/m²) 21.5 ± 2.3 37.7 ± 5.9 <.0001
Waist/height ratio 0.85 ± 0.05 0.95 ± 0.06 <.0001
MAP 75.9 ± 7.72 82.6 ± 8.30 .001
Triglycerides (mg/dL) 71.6 ± 31.7 83.7 ± 35.4 .123
Cholesterol (mg/dL) 155.7 ± 28.3 161.0 ± 23.6 .382
HDL (mg/dL) 52.7 ± 10.7 43.4 ± 8.9 <.0001
LDL (mg/dL) 88.8 ± 25.2 101.0 ± 20.3 .023
HOMA-IR 1.47 ± 0.86 3.78 ± 2.66 <.0001
Fasting insulin (μIU/L) 7.96 ± 4.16 19.99 ± 14.01 <.0001
Fasting glucose (mg/dL) 74.6 ± 7.7 76.5 ± 8.2 .310
Brain tissue volume (mL) 1164 ± 108 1144 ± 141 .510
Intracranial vault volume (mL) 1194 ± 111 1183 ± 144 .728
CSF volume (mL) 29.7 ± 11.1 38.7 ± 20.2 .012

↵a Data are mean ± SD.

↵b SES category ranges from 1 to 5 with higher numbers indicating lower socioeconomic class.